Velo-cardio-facial Syndrome: A Model for Understanding Microdeletion Disorders, Edited by Kieran C. Murphy Education and Research Centre, Royal College of Surgeons of Ireland, Peter J. Scambler Institute of Child Health, University College London.
Velo-Cardio-Facial Syndrome, volume 1 by Robert J. Shprintzen and Karen J. Golding-Kushner (Plural Publishing, 2008)
Velo-Cardio-Facial Syndrome, volume1 is a comprehensive text describing the full range of clinical findings associated with VCFS. The text is accompanied by a DVD that contains 19 videos that compliment the text and more than 110 figures, many in color, including growth charts specific to VCFS. Chapter 1 details the history of VCFS, its delineation, and the current interest in this important syndrome. Chapter 2 details the phenotypic spectrum of VCFS, detailing 190 clinical features of the syndrome with 72 figures associated with the written descriptions. Chapter 3 discusses the genetics of VCFS in straightforward and simple language that is suitable for all readers. Included in Chapter 3 is a description of how the deletion occurs and why it can account for the expansive clinical spectrum. Chapter 4 is a guide for the clinical management of VCFS including triage systems that are specific to the natural history of the syndrome. Chapter 5 provides an important discussion of growth, weight gain, and feeding in VCFS and includes the first growth chart specific to the syndrome. Feeding techniques are discussed, as are the reasons for feeding difficulties in VCFS. The aim of this chapter is to avoid stress and medical dependency that can be better understood based on the growth curves provided.